10 days old

Scientist - Biomarker Discovery Cardiometabolic Disorders

Amgen
South San Francisco, CA 94080
  • Job Code
    116988497
Amgen

Job ID: R-88539
Location: South San Francisco, CA, US 94083

Amgen is a leading global biotechnology company, with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses. Our medicines have made a dramatic difference in the lives of millions. To underpin our commitment to serve patients, Amgen is developing a Biomarker-Discovery group to support therapeutic programs.

The Amgen Cardiometabolic Disorders Therapeutic Area is looking for a Scientist dedicated to biomarker discovery in the areas of cardiovascular disease, metabolic disease, and heart failure. In this role you will work cross-functionally and interact closely with both the clinical biomarker and discovery research groups.

The position will focus on the discovery of biomarkers to support the progression of therapeutic candidates from discovery to early clinical development. The role is responsible for:
  • Developing deep disease area expertise for key indications in the therapeutic area's strategy
  • Working closely with colleagues from deCODE Genetics and Global Development to develop the strategy for human biomarker discovery, validation and development
  • Discovery and prioritization of disease stratification and target engagement biomarker candidates relevant to the pipeline
  • Developing, implementing, and executing a therapeutic biomarker discovery strategy across several programs
  • Generating and transitioning key pharmacodynamic and patient stratification/selection biomarker discovery data in support of clinical biomarker assay and companion diagnostic test development
  • Supporting translational biomarker activities for therapeutic assets including investigator meetings/ad boards and investigator sponsored studies for correlative biomarker research together with the Clinical Biomarker lead


The role is expected to work in a highly matrixed environment to drive scientific and technical innovation collaboratively with other members of the Cardiometabolic Disorders group, as well as with other functions including the Clinical Biomarker & Diagnostics Team, Global Development (both early and late development), Safety Scientists (TSBS), Therapeutic Discovery, deCODE Genetics and Computational Biology.

Basic Qualifications

Doctorate degree

OR

Master's degree and 4 years of scientific experience
OR

Bachelor's degree and 6 years scientific experience

Preferred Qualifications

PhD or MD, with postdoctoral training and research experience in the fields of cell and molecular biology or biochemistry

Demonstrated track record of independent critical thinking and scientific achievement in the areas of cell and molecular biology and biochemistry as demonstrated by multiple high impact publications

Demonstrated experience in leading independent research and/or drug development

Experience with implementing multiple technology platforms

Experience with computational biology

Strong verbal and written communication skills. Ability to collaborate and troubleshoot to solve problems

Experience working in teams and consistently delivering results

Our culture is what makes Amgen a special place to work. We have a powerful shared purpose around our mission - to serve patients. We respect one another, recognize contributions, and have embedded collaboration, trust, empowerment and inclusion in all that we do.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.

PI116988497

<b>Amgen</b><br/><br/><b>Job ID: </b>R-88539<br/><b>Location: </b>South San Francisco, CA, US 94083<br/><br/>Amgen is a leading global biotechnology company, with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses. Our medicines have made a dramatic difference in the lives of millions. To underpin our commitment to serve patients, Amgen is developing a Biomarker-Discovery group to support therapeutic programs.<br><br>The Amgen Cardiometabolic Disorders Therapeutic Area is looking for a Scientist dedicated to biomarker discovery in the areas of cardiovascular disease, metabolic disease, and heart failure. In this role you will work cross-functionally and interact closely with both the clinical biomarker and discovery research groups.<br><br>The position will focus on the discovery of biomarkers to support the progression of therapeutic candidates from discovery to early clinical development. The role is responsible for:<br><ul><li>Developing deep disease area expertise for key indications in the therapeutic area's strategy</li><li>Working closely with colleagues from deCODE Genetics and Global Development to develop the strategy for human biomarker discovery, validation and development</li><li>Discovery and prioritization of disease stratification and target engagement biomarker candidates relevant to the pipeline</li><li>Developing, implementing, and executing a therapeutic biomarker discovery strategy across several programs</li><li>Generating and transitioning key pharmacodynamic and patient stratification/selection biomarker discovery data in support of clinical biomarker assay and companion diagnostic test development</li><li>Supporting translational biomarker activities for therapeutic assets including investigator meetings/ad boards and investigator sponsored studies for correlative biomarker research together with the Clinical Biomarker lead</li></ul><br><br>The role is expected to work in a highly matrixed environment to drive scientific and technical innovation collaboratively with other members of the Cardiometabolic Disorders group, as well as with other functions including the Clinical Biomarker & Diagnostics Team, Global Development (both early and late development), Safety Scientists (TSBS), Therapeutic Discovery, deCODE Genetics and Computational Biology.<br><br><b>Basic Qualifications</b><br><br>Doctorate degree<br><br>OR<br><br>Master's degree and 4 years of scientific experience<br>OR<br><br>Bachelor's degree and 6 years scientific experience<br><br><b>Preferred Qualifications</b><br><br>PhD or MD, with postdoctoral training and research experience in the fields of cell and molecular biology or biochemistry<br><br>Demonstrated track record of independent critical thinking and scientific achievement in the areas of cell and molecular biology and biochemistry as demonstrated by multiple high impact publications<br><br>Demonstrated experience in leading independent research and/or drug development<br><br>Experience with implementing multiple technology platforms<br><br>Experience with computational biology<br><br>Strong verbal and written communication skills. Ability to collaborate and troubleshoot to solve problems<br><br>Experience working in teams and consistently delivering results<br><br>Our culture is what makes Amgen a special place to work. We have a powerful shared purpose around our mission - to serve patients. We respect one another, recognize contributions, and have embedded collaboration, trust, empowerment and inclusion in all that we do. <br><br>Join Us <br> <br> If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen. <br> <br> Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses. <br> <br> As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients. <br> <br> Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. <br> <br> Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.<br/><br/> <img src="https://analytics.click2apply.net/v/2Vll24SW5NYzTZVPFDBKj"> <p>PI116988497</p>

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Posted: 2020-01-10 Expires: 2020-02-10

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Scientist - Biomarker Discovery Cardiometabolic Disorders

Amgen
South San Francisco, CA 94080

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