11 days old

Principal Scientist - Immuno-Oncology and Inflammation Research

Amgen
South San Francisco, CA 94080
  • Job Code
    115093816
Amgen

Job ID: R-87097
Location: South San Francisco, CA, US 94083

The Department of Oncology and Inflammation Research is seeking a highly motivated Principal Scientist to investigate mechanisms underlying the pathogenesis of autoimmune and inflammatory diseases with the goal to develop novel immune-modulatory therapies to treat chronic inflammatory diseases and cancer.

In this role you will independently lead a group as well as project teams to discover and validate new therapeutic targets. You will also collaborate with other research scientists at multiple Amgen sites, including teams in other functional areas such as Oncology, Therapeutic Discovery, Medical Sciences and Computational Biology. In this position, the individual is expected to make major scientific laboratory-based contributions to the research goals and milestones of the Oncology and Inflammation therapeutic areas.

Job Responsibilities

Perform cutting-edge research that integrates human genetics, immunology and oncology

Develop novel immune-modulating therapies using various innovative technologies and approaches

Manage projects from early discovery through therapeutic development

Publish experimental findings in top-tier Journals and present novel findings at national and international conferences

Basic Qualifications

Doctorate degree and 3 years of Scientific experience

OR

Master's degree and 6 years of scientific experience

OR

Bachelor's degree and 8 years of scientific experience

Preferred Qualifications

PhD or MD, with postdoctoral training and research experience in the fields of immunology, oncology, cancer immunotherapy, molecular biology, stem cell biologyor human genetics

Demonstrated track record of independent critical thinking and scientific achievement in the areas of immunology or oncology as demonstrated by multiple high impact publications

Demonstrated track record of independent target discovery and successful therapeutic development

Technical expertise in one or more of the following areas: 1. Multi-color flow cytometry, 2. complex cell-based functional assays, 3. 3D organoid cultures, 4. genetic manipulation of cell lines and/or primary cells, 5. analysis of gene regulation at the single cell level, 6. cell signaling/biochemistry,7. in vivo mouse models of disease, 8. bioinformatics analysis

Strong verbal and written communication skills

Ability to collaborate and troubleshoot to solve problems

At Amgen, our mission is serving patients. Our staff are dedicated to pushing the boundaries of science to transform medicine and turn the tide on serious illnesses. Central to achieving this mission is our "people-first" philosophy. We recruit the best talent, build an environment that facilitates career growth, and provide staff with the opportunity to make significant contributions for patients and our business.

Consistent with our core leadership value of "Develops the Best Team," we are seeking leaders that prioritize the development of talent. As a manager, your first priority and primary role is to accelerate the performance and development of your team. We expect managers to exemplify strong leadership and champion self-awareness and career development. Ways that you will display your leadership acumen in this role include:
  • Mentoring, coaching, and developing staff to build highly-skilled, diverse, and inclusive teams
  • Fostering a positive and respectful work environment that encourages staff retention and motivates individuals to work toward common goals and priorities
  • Ensuring that staff understand how their efforts and contributions make a meaningful impact to the business
  • Growing core skills and capabilities among staff, particularly in learning agility, problem solving, strategic and creative thinking, flexibility, resilience, effective communication, prioritization, delivery of results, and continuous improvement
  • Making accurate evaluations of your team's skills and competencies and providing timely and respectful feedback, including direct delivery of difficult messages
  • Developing an understanding of your team's career objectives and serve as a thought-partner in their career development plans


Am gen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives.Our culture is what makes Amgen a special place to work. We have a powerful shared purpose around our mission - to serve patients. We respect one another, recognize contributions, and have embedded collaboration, trust, empowerment and inclusion in all that we do.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.

PI115093816

<b>Amgen</b><br/><br/><b>Job ID: </b>R-87097<br/><b>Location: </b>South San Francisco, CA, US 94083<br/><br/>The Department of Oncology and Inflammation Research is seeking a highly motivated Principal Scientist to investigate mechanisms underlying the pathogenesis of autoimmune and inflammatory diseases with the goal to develop novel immune-modulatory therapies to treat chronic inflammatory diseases and cancer.<br><br>In this role you will independently lead a group as well as project teams to discover and validate new therapeutic targets. You will also collaborate with other research scientists at multiple Amgen sites, including teams in other functional areas such as Oncology, Therapeutic Discovery, Medical Sciences and Computational Biology. In this position, the individual is expected to make major scientific laboratory-based contributions to the research goals and milestones of the Oncology and Inflammation therapeutic areas.<br><br><b>Job Responsibilities </b><br><br>Perform cutting-edge research that integrates human genetics, immunology and oncology<br><br>Develop novel immune-modulating therapies using various innovative technologies and approaches<br><br>Manage projects from early discovery through therapeutic development<br><br>Publish experimental findings in top-tier Journals and present novel findings at national and international conferences<br><br><b>Basic Qualifications</b><br><br>Doctorate degree and 3 years of Scientific experience<br><br>OR<br><br>Master's degree and 6 years of scientific experience<br><br>OR<br><br>Bachelor's degree and 8 years of scientific experience<br><br><b>Preferred Qualifications</b><br><br>PhD or MD, with postdoctoral training and research experience in the fields of immunology, oncology, cancer immunotherapy, molecular biology, stem cell biologyor human genetics<br><br>Demonstrated track record of independent critical thinking and scientific achievement in the areas of immunology or oncology as demonstrated by multiple high impact publications<br><br>Demonstrated track record of independent target discovery and successful therapeutic development<br><br>Technical expertise in one or more of the following areas: 1. Multi-color flow cytometry, 2. complex cell-based functional assays, 3. 3D organoid cultures, 4. genetic manipulation of cell lines and/or primary cells, 5. analysis of gene regulation at the single cell level, 6. cell signaling/biochemistry,7. in vivo mouse models of disease, 8. bioinformatics analysis<br><br>Strong verbal and written communication skills<br><br>Ability to collaborate and troubleshoot to solve problems<br><br>At Amgen, our mission is serving patients. Our staff are dedicated to pushing the boundaries of science to transform medicine and turn the tide on serious illnesses. Central to achieving this mission is our "people-first" philosophy. We recruit the best talent, build an environment that facilitates career growth, and provide staff with the opportunity to make significant contributions for patients and our business.<br><br>Consistent with our core leadership value of "Develops the Best Team," we are seeking leaders that prioritize the development of talent. As a manager, your first priority and primary role is to accelerate the performance and development of your team. We expect managers to exemplify strong leadership and champion self-awareness and career development. Ways that you will display your leadership acumen in this role include:<br><ul><li>Mentoring, coaching, and developing staff to build highly-skilled, diverse, and inclusive teams</li><li>Fostering a positive and respectful work environment that encourages staff retention and motivates individuals to work toward common goals and priorities</li><li>Ensuring that staff understand how their efforts and contributions make a meaningful impact to the business</li><li>Growing core skills and capabilities among staff, particularly in learning agility, problem solving, strategic and creative thinking, flexibility, resilience, effective communication, prioritization, delivery of results, and continuous improvement</li><li>Making accurate evaluations of your team's skills and competencies and providing timely and respectful feedback, including direct delivery of difficult messages</li><li>Developing an understanding of your team's career objectives and serve as a thought-partner in their career development plans</li></ul><br><br>Am gen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives.Our culture is what makes Amgen a special place to work. We have a powerful shared purpose around our mission - to serve patients. We respect one another, recognize contributions, and have embedded collaboration, trust, empowerment and inclusion in all that we do. <br><br>Join Us <br> <br> If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen. <br> <br> Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses. <br> <br> As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients. <br> <br> Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. <br> <br> Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.<br/><br/> <img src="https://analytics.click2apply.net/v/LYWgQBsq14LkIB74iq27g"> <p>PI115093816</p>

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Posted: 2019-11-02 Expires: 2019-12-03

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Principal Scientist - Immuno-Oncology and Inflammation Research

Amgen
South San Francisco, CA 94080

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