16 days old

Associate Scientist - Medicinal Chemistry

Amgen
Thousand Oaks, CA 91360
  • Job Code
    115164593
Amgen

Job ID: R-87234
Location: Thousand Oaks, CA, US 91360

The Associate Scientist will be part of an innovative Medicinal Chemistry group, with responsibilities including the synthesis and purification of novel compounds for potential clinical drug development, including opportunity to work within Amgen's Induced Proximity Platform (IPP), which is focused on novel and innovative approaches to modulate intractable targets in diseases using the emerging PROTAC modality. The Associate Scientist will work in teams to develop, implement and perform organic reactions for ongoing Medicinal Chemistry programs, including the troubleshooting of synthetic routes and reactions, as well as the scouting of new synthetic routes. This individual will perform structural determinations using NMR and mass spectral techniques and purify compounds using a variety of modern techniques. Additional responsibilities include maintaining laboratory notebooks, participating in group and project meetings, presenting to groups and aiding in the writing of papers and patent applications.

Basic Qualifications
  • Master's degree and 2 years of scientific experience OR
  • Bachelor's degree and 4 years of scientific experience


Preferred Qualifications
  • 2+ years of focus or specialization in synthetic organic or medicinal chemistry (academic and/or industrial)
  • Demonstrated ability to scout and troubleshoot synthetic routes
  • Demonstration of good lab practices, with particular attention to safety
  • Knowledge of the application of parallel synthesis techniques to medicinal chemistry a plus
  • Clear understanding of structural determination using NMR and Mass Spectral techniques as well as knowledge of purification methods
  • Ability to work well in teams
  • Excellent communication skills (both written and oral)


Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology and is matched by an unparalleled toolbox of therapeutic modalities ranging from small molecules to peptides to proteins to antibodies to live-cell therapies.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

PI115164593

<b>Amgen</b><br/><br/><b>Job ID: </b>R-87234<br/><b>Location: </b>Thousand Oaks, CA, US 91360<br/><br/>The Associate Scientist will be part of an innovative Medicinal Chemistry group, with responsibilities including the synthesis and purification of novel compounds for potential clinical drug development, including opportunity to work within Amgen's Induced Proximity Platform (IPP), which is focused on novel and innovative approaches to modulate intractable targets in diseases using the emerging PROTAC modality. The Associate Scientist will work in teams to develop, implement and perform organic reactions for ongoing Medicinal Chemistry programs, including the troubleshooting of synthetic routes and reactions, as well as the scouting of new synthetic routes. This individual will perform structural determinations using NMR and mass spectral techniques and purify compounds using a variety of modern techniques. Additional responsibilities include maintaining laboratory notebooks, participating in group and project meetings, presenting to groups and aiding in the writing of papers and patent applications.<br><br><b>Basic Qualifications </b><br><ul><li>Master's degree and 2 years of scientific experience OR</li><li>Bachelor's degree and 4 years of scientific experience</li></ul><br><br><b>Preferred Qualifications </b><br><ul><li>2+ years of focus or specialization in synthetic organic or medicinal chemistry (academic and/or industrial)</li><li>Demonstrated ability to scout and troubleshoot synthetic routes</li><li>Demonstration of good lab practices, with particular attention to safety</li><li>Knowledge of the application of parallel synthesis techniques to medicinal chemistry a plus</li><li>Clear understanding of structural determination using NMR and Mass Spectral techniques as well as knowledge of purification methods</li><li>Ability to work well in teams</li><li>Excellent communication skills (both written and oral)</li></ul><br><br>Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.<br><br>Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology and is matched by an unparalleled toolbox of therapeutic modalities ranging from small molecules to peptides to proteins to antibodies to live-cell therapies.<br><br>Join Us <br> <br> If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen. <br> <br> Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses. <br> <br> As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients. <br> <br> Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.<br/><br/> <img src="https://analytics.click2apply.net/v/eoNoNVUeN5jBTjxYhdXDl"> <p>PI115164593</p>

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Posted: 2019-11-05 Expires: 2019-12-06

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Associate Scientist - Medicinal Chemistry

Amgen
Thousand Oaks, CA 91360

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